Rituximab as Rescue Therapy for Aggressive Pediatric Multiple Sclerosis

Rituximab as Rescue Therapy for Aggressive Pediatric Multiple Sclerosis

Blog Article

Multiple sclerosis is a chronic, debilitating disease.Almost one in ten patients with MS has a history of disease onset during childhood.Although numerous therapeutic options PRO BEAUTY POWDER exist for adult MS, the available treatments for pediatric patients are still limited.

One of the emerging therapies is rituximab, a monoclonal anti-CD20 chimeric antibody that can deplete the CD20+ lymphocyte populations.A 12-year-old boy presented with ataxia, Applique Tools paresthesias, and headache while his brain MRI showed numerous T2 contrast-enhancing lesions.Gamma globulin, steroids, and cyclophosphamide failed to intercept his disease, and he progressed to a rapid clinical and radiological deterioration.

Treatment with rituximab reversed the disease course in a dramatic fashion, leading to complete remission.